The Centre for Endocrine, Diabetes and Obesity Research (CEDOR) is a specialist research unit based in the Endocrine and Diabetes Service at Wellington Regional Hospital. The unit, which is led by Principal Investigator, Associate Professor Jeremy Krebs, was established in 1998, and has grown to encompass 11 permanent staff members with input from clinical staff from both Endocrine and Diabetes specialities. The unit also supervises students, both MSc and PhD, offers periodic summer studentships and helps with the training of senior medical staff.
CEDOR conducts a broad range of clinical trials looking at both new medications for Type 1 and 2 Diabetes as well as the effects of diet and lifestyle choices and surgery for obesity on health. Investigator-led research is a strong focus for us, with Assoc. Prof. Krebs having been awarded several HRC grants.
CEDOR also has a long established involvement in Phase 3 and 4 pharmaceutical trials for diabetes. Involvement in all our trials provides people with close medical supervision by our experienced and friendly team of doctors and nurses. Our researchers publish articles and studies in scientific journals and present at conferences in NZ and overseas.
CEDOR conducts research in the following areas:
- Iodine, Sodium
- Blood Pressure
- Dietary interventions in type 1 and type 2 diabetes
- Pharmaceutical Trials
- Investigations of a gestational diabetes cohort
- Investigations of a post-gastric bypass cohort
- Metabolic physiology
- Obesity prevention
Recent journal articles published by CEDOR members
This list is not a complete list of all publications, but ones available to be viewed on PubMed.
McTavish L, Krebs JD, Weatherall M, Wiltshire E. Weight-based hypoglycaemia treatment protocol for adults with Type 1 diabetes: a randomized crossover clinical trial.Diabet Med. 2015 Sep;32(9):1143-8 https://www.ncbi.nlm.nih.gov/pubmed/25683747
Krebs JD, Parry-Strong A, Cresswell P, Reynolds AN, Hanna A, Haeusler S. A randomised trial of a carbohydrate restricted diet vs standard carbohydrate counting in adults with type 1 diabetes. Asia Pac J Clin Nutr 2016;25(1):78-84 https://www.ncbi.nlm.nih.gov/pubmed/26965765
Cresswell P, Krebs JK, Gilmour J, Hanna A, Parry-Strong A.From ‘pleasure to chemistry’: the experience of carbohydrate counting with and without carbohydrate restriction for people with Type 1 diabetes. Journal of Primary Healthcare 2015;7(4):291–298. http://www.ncbi.nlm.nih.gov/pubmed/26668834
Whitfield P, Parry-Strong A, Walsh E, Weatherall M, Krebs JD. The effect of a cinnamon, chromium and magnesium formulated honey on glycaemic control, weight loss and lipid parameters in Type 2 diabetes: An open-label cross-over randomised controlled trial. European Journal of Nutrition 2015 on line DOI 10.1007/s00394-015-0926-x http://www.ncbi.nlm.nih.gov/pubmed/25986159
Gendall P, Hoek J, Taylor R, Mann J, Krebs J, Parry-Strong A. Should support for obesity interventions or perceptions of their perceived effectiveness shape policy? Aust N Z J Public Health. 2015 Apr;39(2):172-6. doi: 10.1111/1753-6405.12319. Epub 2015 Feb 25. http://www.ncbi.nlm.nih.gov/pubmed/25716535
Haeusler S, Parry-Strong A, Krebs JD. The prevalence of low vitamin B12 status in people with type 2 diabetes receiving metformin therapy in New Zealand—a clinical audit. New Zealand Medical Journal 2014; vol-127-no-1404-17-oct-2014/6326 http://www.ncbi.nlm.nih.gov/pubmed/25331307
Carroll RW, Hall RM, Parry-Strong A, Wilson JM, Krebs JD. Therapeutic Options in the Management of Obesity. New Zealand Medical Journal. 22 November 2013, Vol 126 No 1386; ISSN 1175 8716 http://www.ncbi.nlm.nih.gov/pubmed/24316994
J.D. Krebs, A. Parry-Strong, E. Gamble, L. McBain, L.J. Bingham, E.S. Dutton, S. Tapu-Ta’ala, J. Howells, H. Metekingi, R.B.W. Smith, K.J. Coppell. A structured, group-based diabetes self-management education (DSME) programme for people, families and whanau with type 2 diabetes (T2DM) in New Zealand: An observational study. Primary Care Diabetes 2013 Mar 18p S1751-9918(13) http://www.ncbi.nlm.nih.gov/pubmed/23517821
Krebs JD, Bell D, Hall R, Parry-Strong A, Docherty P, Clarke K, Chase JG. Improvements in Glucose Metabolism and Insulin Sensitivity with a Low-Carbohydrate Diet in Obese Patients with Type 2 Diabetes. Journal of the American College of Nutrition 2013; 32(1): 11-17 http://www.ncbi.nlm.nih.gov/pubmed/24015695
Krebs JD, Parry-Strong A, Weatherall M, Carroll RW, Downie M. A cross-over study of the acute effects of espresso coffee on glucose tolerance and insulin sensitivity in people with type 2 diabetes mellitus. Metabolism: Clinical and Experimental 2012; 61 (9): 1231-1237 http://www.ncbi.nlm.nih.gov/pubmed/22459614
J. D. Krebs, C. R. Elley, A. Parry-Strong, H. Lunt, P. L. Drury, D. A. Bell, E. Robinson, S. A. Moyes and J. I. Mann. The Diabetes Excess Weight Loss (DEWL) Trial: a randomised controlled trial of high-protein versus high-carbohydrate diets over 2 years in type 2 diabetes. Diabetologia: Volume 55, Issue 4 (2012), Page 905-914 http://www.ncbi.nlm.nih.gov/pubmed/22286528