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SELECTION

Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Ulcerative Colitis

This study is currently recruiting participants.

Trial website: https://clinicaltrials.gov/ct2/show/NCT02914522?term=ulcerative+colitis+filgotinib&rank=2 

Trial purpose: The primary objectives of this study are to evaluate the safety and efficacy of filgotinib in the induction and maintenance treatment of moderately to severely active ulcerative colitis (UC) in participants who are biologic-naive and biologic-experienced.

Participants who complete the study, or do not meet protocol response or remission criteria at Week 10 will have the option to enter a separate, long-term extension (LTE) study (Gilead Study GS-US-418-3899).

SELECTIONLTE

Filgotinib in Long-Term Extension Study of Adults With Ulcerative Colitis (SELECTIONLTE)

This study is currently recruiting participants.

Trial website: https://clinicaltrials.gov/ct2/show/NCT02914535?term=ulcerative+colitis+filgotinib&rank=1

Trial purpose: The primary objective of this study is to observe the long-term safety of filgotinib in adults who have completed or met protocol specified efficacy discontinuation criteria in a prior Gilead-sponsored filgotinib treatment study in ulcerative colitis (UC).

DIVERSITY

Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

This study is currently recruiting participants.

Trial website: https://clinicaltrials.gov/ct2/show/NCT02914561?term=crohns+disease+filgotinib&rank=2

Trial purpose: The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active Crohn's disease (CD) in participants who are biologic-naive and biologic-experienced.

Participants who complete the study, or do not meet protocol response or remission criteria at Week 10 will have the option to enter a separate long-term extension (LTE) study (Gilead Study GS-US-419-3896).

DIVERSITYLTE

Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease

This study is currently recruiting participants.

Trial website: https://clinicaltrials.gov/ct2/show/NCT02914600?term=crohns+disease+filgotinib&rank=1 

Trial purpose: The primary objective of this study is to observe the long-term safety of filgotinib in adults who have completed or met protocol specified efficacy discontinuation criteria in a prior Gilead-sponsored filgotinib treatment study in Crohn's disease (CD). 

PTG-100

Safety and Efficacy Study of PTG-100 in the Treatment of Moderate to Severe Ulcerative Colitis

This study is currently recruiting participants.

Trial website: https://clinicaltrials.gov/ct2/show/study/NCT02895100?term=ptg-100&rank=1#contacts 

Trial purpose: The main objectives of this study are to evaluate the efficacy, safety, and tolerability of daily doses of PTG-100 in subjects with moderate to severe ulcerative colitis (UC).

Last updated 8 August 2017.